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Developmental mechanisms and adult stem cells for therapeutic lung regeneration.

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Chronic degenerative lung diseases are essentially untreatable pathological conditions. By contrast, the healthy lung has numerous mechanisms that allow for rapid repair and restoration of function following minor acute injuries.… Click to show full abstract

Chronic degenerative lung diseases are essentially untreatable pathological conditions. By contrast, the healthy lung has numerous mechanisms that allow for rapid repair and restoration of function following minor acute injuries. We discuss the normal endogenous processes of lung development, homeostatic maintenance and repair and consider the research strategies required for the development of methods for human therapeutic lung regeneration.

Keywords: regeneration developmental; developmental mechanisms; lung regeneration; therapeutic lung; lung

Journal Title: Developmental biology
Year Published: 2018

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