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Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O2-regulated HIF-1α subunit… Click to show full abstract
Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O2-regulated HIF-1α subunit and a constitutively expressed HIF-1β subunit. This review provides a compendium of proteins that interact with the HIF-1α subunit, many of which regulate HIF-1 activity in either an O2-dependent or O2-independent manner.
Keywords:
hif;
interact hif;
hif subunit;
compendium proteins;
proteins interact
Journal Title: Experimental cell research
Year Published: 2017
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Journal Title: Experimental cell research
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!