LAUSR

This study was conducted in compliance with facility SOPs and AAALAC standards for the use of animals in biomedical research following IACUC approval. Eleven (11) adult males ranging in weight from 5-7 kg were enrolled in the study. The staged study design that permitted refinement of data acquisition, implantation procedures and catheter design and placement are detailed in Table 1. Telemetry data acquisition was conducted at progressive stages of test system optimization. At data acquisition time points systemic blood pressure (BP), left ventricular pressure (LVP), heart rate (HR) and electrocardiogram (ECG) parameters were determined. Systemic BP, LVP and HR are the cardinal parameters discussed here.