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Mo1135 – Role of Reflux in the Pathogenesis of Eosinophilic Esophagitis - Comprehensive Appraisal with Off- and On-Ppi Impedance-Ph Monitoring

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METHODS: Prospective multicenter study comparing EoE patients with healthy controls and gastroesophageal reflux disease cases. Patients with EoE were evaluated offand on PPI; responsiveness was assessed by histology. Impedance-pH appraisal… Click to show full abstract

METHODS: Prospective multicenter study comparing EoE patients with healthy controls and gastroesophageal reflux disease cases. Patients with EoE were evaluated offand on PPI; responsiveness was assessed by histology. Impedance-pH appraisal included chemical clearance, assessed with the postreflux swallow-induced peristaltic wave (PSPW) index, and mucosal integrity measured with mean nocturnal baseline impedance (MNBI).

Keywords: pathogenesis eosinophilic; appraisal; reflux pathogenesis; impedance; mo1135 role; role reflux

Journal Title: Gastroenterology
Year Published: 2019

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