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VAGUS NERVE STIMULATION REQUIRES BOTH IPSILATERAL AND CONTRALATERAL EFFERENT VAGAL ACTIVITY TO FULLY EXERT ITS CARDIOPROTECTION AGAINST CARDIAC ISCHEMIA/REPERFUSION INJURY

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Background: Vagus nerve stimulation (VNS) has been shown to exert cardioprotection against cardiac ischemia/reperfusion (I/R) injury. However, whether the benefit of VNS is mainly due to direct activation of ipsilateral… Click to show full abstract

Background: Vagus nerve stimulation (VNS) has been shown to exert cardioprotection against cardiac ischemia/reperfusion (I/R) injury. However, whether the benefit of VNS is mainly due to direct activation of ipsilateral vagal fibers or indirect activation of the contralateral vagal trunk remains

Keywords: cardioprotection cardiac; nerve stimulation; cardiac ischemia; vagus nerve; exert cardioprotection; ischemia reperfusion

Journal Title: Journal of the American College of Cardiology
Year Published: 2017

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