Background: Despite more than 200 years of clinical experience and a pivotal trial, recently published research has called into question the safety and efficacy of digoxin therapy in heart failure… Click to show full abstract
Background: Despite more than 200 years of clinical experience and a pivotal trial, recently published research has called into question the safety and efficacy of digoxin therapy in heart failure (HF). Methods: HF-ACTION enrolled 2331 outpatients with HF and an EF <35% and randomized them to
               
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