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RATIONALE AND METHODS OF THE PROSPECTIVE STUDY OF BIOMARKERS, SYMPTOM IMPROVEMENT AND VENTRICULAR REMODELING DURING ENTRESTO THERAPY FOR HEART FAILURE (PROVE-HF) STUDY

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Background: Therapy with sacubitril/valsartan improves outcome in those with heart failure with reduced ejection fraction (HFrEF). Questions remain regarding effect of sacubitril/valsartan on left ventricular (LV) remodeling as well as… Click to show full abstract

Background: Therapy with sacubitril/valsartan improves outcome in those with heart failure with reduced ejection fraction (HFrEF). Questions remain regarding effect of sacubitril/valsartan on left ventricular (LV) remodeling as well as its effects on circulating biomarkers (including B-type

Keywords: ventricular remodeling; therapy; study; heart failure

Journal Title: Journal of the American College of Cardiology
Year Published: 2017

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