LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

COLCHICINE EXERTS ANTITHROMBOTIC PROPERTIES IN OXLDL-TREATED ENDOTHELIAL CELLS VIA INHIBITION OF TISSUE FACTOR EXPRESSION AND ACTIVITY

Photo by nci from unsplash

Background: Tissue factor (TF) exposure is the key trigger of thrombus formation. Oxidized low-density lipoproteins (oxLDL) induce TF in endothelial cells (ECs), suggesting that oxLDL may act locally promoting thrombosis… Click to show full abstract

Background: Tissue factor (TF) exposure is the key trigger of thrombus formation. Oxidized low-density lipoproteins (oxLDL) induce TF in endothelial cells (ECs), suggesting that oxLDL may act locally promoting thrombosis in atherosclerotic lesions. Colchicine (COL) is an anti-inflammatory agent that

Keywords: exerts antithrombotic; endothelial cells; tissue factor; colchicine exerts

Journal Title: Journal of the American College of Cardiology
Year Published: 2017

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.