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VENTRICULAR ARRHYTHMIAS IN PATIENTS MANAGED WITH IBRUTINIB FOR CANCER IMMUNOTHERAPY

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Ibrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor associated with dramatic improvements in outcomes of various B-cell hematologic malignancies and is now standard therapy. However, Ibrutinib is associated with… Click to show full abstract

Ibrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor associated with dramatic improvements in outcomes of various B-cell hematologic malignancies and is now standard therapy. However, Ibrutinib is associated with a >4-fold increased risk of incident atrial arrhythmias. Recently, an alarming

Keywords: managed ibrutinib; patients managed; arrhythmias patients; ventricular arrhythmias; ibrutinib cancer; arrhythmias

Journal Title: Journal of the American College of Cardiology
Year Published: 2018

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