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Cytochrome P450 2C19 (CYP2C19) is a hepatic enzyme involved in metabolism of clopidogrel to its active metabolite. Polymorphisms with 2 loss-of-function (LOF) alleles lead to poor metabolism of clopidogrel, but… Click to show full abstract
Cytochrome P450 2C19 (CYP2C19) is a hepatic enzyme involved in metabolism of clopidogrel to its active metabolite. Polymorphisms with 2 loss-of-function (LOF) alleles lead to poor metabolism of clopidogrel, but little is known about the effects of both heterozygous state for LOF and gain-of-function
Keywords:
outcomes euclid;
cardiology;
cyp2c19 status;
status outcomes;
euclid trial;
cyp2c19
Journal Title: Journal of the American College of Cardiology
Year Published: 2018
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Journal Title: Journal of the American College of Cardiology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!