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SUBSEQUENT CHANGES IN DOSING REQUIREMENTS TO PRODUCE THERAPEUTIC ANTICOAGULATION WITH INJECTABLE DIRECT THROMBIN INHIBITORS AFTER INSTITUTIONAL CHANGE TO THE ACTIVATED PARTIAL THROMBOPLASTIN TIME REAGENT

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Injectable direct thrombin inhibitors (iDTI) argatroban and bivalirudin are useful in the management of patients with documented or suspected heparin induced thrombocytopenia (HIT). Management of iDTIs includes monitoring with the… Click to show full abstract

Injectable direct thrombin inhibitors (iDTI) argatroban and bivalirudin are useful in the management of patients with documented or suspected heparin induced thrombocytopenia (HIT). Management of iDTIs includes monitoring with the activated partial thromboplastin time (aPTT) and dose adjustment to a

Keywords: thromboplastin time; direct thrombin; injectable direct; thrombin inhibitors; partial thromboplastin; activated partial

Journal Title: Journal of the American College of Cardiology
Year Published: 2018

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