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FAMILIAL HYPERCHOLESTEREMIA: WHEN STATINS, EZETIMIBE & PCSK9 INHIBITORS ARE NOT ENOUGH

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Patients with familial hypercholesteremia (FH) require lipoprotein aphaeresis (LA), mipomersen or lomitapide to control their LDL-C. Proprotein convertase subtisilin kexin type 9 (PCSK9) inhibitors have reduced the use of these… Click to show full abstract

Patients with familial hypercholesteremia (FH) require lipoprotein aphaeresis (LA), mipomersen or lomitapide to control their LDL-C. Proprotein convertase subtisilin kexin type 9 (PCSK9) inhibitors have reduced the use of these treatment strategies but some FH patients still require additional LDL-C

Keywords: statins ezetimibe; pcsk9 inhibitors; hypercholesteremia statins; ezetimibe pcsk9; familial hypercholesteremia

Journal Title: Journal of the American College of Cardiology
Year Published: 2018

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