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THE SGLT2 INHIBITOR EMPAGLIFLOZIN CAUSES A GREATER REDUCTION IN SKIN SODIUM CONTENT AND INTERSTITIAL VOLUME THAN LOOP DIURETICS IN HEART FAILURE

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The classic view that sodium (Na) in the extracellular volume (both intravascular and interstitial spaces) is in equilibrium has been recently challenged with the discovery of skin Na storage at… Click to show full abstract

The classic view that sodium (Na) in the extracellular volume (both intravascular and interstitial spaces) is in equilibrium has been recently challenged with the discovery of skin Na storage at higher concentrations than in blood. In fact, skin Na is higher in hypertensive patients than controls

Keywords: volume; causes greater; sglt2 inhibitor; sodium; inhibitor empagliflozin; empagliflozin causes

Journal Title: Journal of the American College of Cardiology
Year Published: 2020

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