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Synthesis of biaryls using palladium nanoparticles immobilized on peptide nanofibers as catalyst and hydroxybenzotriazole as novel phenylating reagent

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Peptide nanofibers decorated with palladium nanoparticles catalyzed direct coupling of aryl halides with hydroxybenzotriazole to afford the corresponding biaryls in good to excellent yields. The coupling reactions proceeded under simple,… Click to show full abstract

Peptide nanofibers decorated with palladium nanoparticles catalyzed direct coupling of aryl halides with hydroxybenzotriazole to afford the corresponding biaryls in good to excellent yields. The coupling reactions proceeded under simple, green, and mild conditions. The peptide nanofibers were used as recyclable supports in the coupling reactions. This approach is the first to use hydroxybenzotriazole as a phenylating agent.

Keywords: biaryls using; peptide nanofibers; synthesis biaryls; palladium nanoparticles

Journal Title: Chinese Journal of Catalysis
Year Published: 2017

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