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Surgical site infection rates are higher among elective colorectal surgery patients receiving non-beta-lactam-based antimicrobial prophylaxis: A retrospective chart review.

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Abstract We compared the odds of acquiring surgical site infection (SSI) for clean-contaminated colorectal surgeries between intravenous β-lactam–based prophylaxis (BLP) versus alternative antimicrobial prophylaxis (AAP). We calculated the odds of… Click to show full abstract

Abstract We compared the odds of acquiring surgical site infection (SSI) for clean-contaminated colorectal surgeries between intravenous β-lactam–based prophylaxis (BLP) versus alternative antimicrobial prophylaxis (AAP). We calculated the odds of acquiring an SSI using logistic regression; adjusted odds ratios (ORs) with 95% confidence intervals (CIs) are reported. Increased odds of SSI were detected with AAP versus BLP (OR, 2.15; 95% CI, 1.33–3.50; P = .002).

Keywords: infection; lactam based; site infection; antimicrobial prophylaxis; surgical site

Journal Title: Infection control and hospital epidemiology
Year Published: 2022

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