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Factors influencing the use of highly bioavailable oral antibiotic therapy for the treatment of prosthetic joint infections

Abstract We conducted a retrospective cohort study to identify factors influencing intravenous (IV) versus oral antibiotic therapy in first-episode prosthetic joint infections. Of the 34/78 (44%) cases treated intravenously, negative… Click to show full abstract

Abstract We conducted a retrospective cohort study to identify factors influencing intravenous (IV) versus oral antibiotic therapy in first-episode prosthetic joint infections. Of the 34/78 (44%) cases treated intravenously, negative cultures (26%), concomitant infections necessitating IV antibiotics (21%), and delays in susceptibility testing (15%) were the most common reasons for IV therapy.

Keywords: antibiotic therapy; oral antibiotic; prosthetic joint; joint infections; factors influencing

Journal Title: Infection Control and Hospital Epidemiology
Year Published: 2024

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