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Synthesizing quantitative and qualitative information on multiple comparisons of health interventions to facilitate knowledge transfer: an example from an EUnetHTA multi-HTA

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Abstract Objective Presenting an approach to synthesize quantitative and qualitative information from systematic reviews of multiple health interventions. Methods Within the context of an EUnetHTA multi-health technology assessment of twenty-three… Click to show full abstract

Abstract Objective Presenting an approach to synthesize quantitative and qualitative information from systematic reviews of multiple health interventions. Methods Within the context of an EUnetHTA multi-health technology assessment of twenty-three surgical techniques, we developed synthetic single tables, using color gradients and abbreviations, with information on which technologies had been compared, estimates of the size of differences for available comparisons, their clinical relevance, and certainty of the related evidence. Results The proposed methodology provided, through a single depiction, information normally included in multiple figures/tables such as network plots, league tables, and summary of findings tables. Conclusion Transferring information on benefits, risks, and certainty of the available evidence on health interventions may be challenging, especially when assessing multiple treatments: more pieces of information need to be integrated in order to show an overall picture for each of the chosen outcomes, and usual reporting tools may be targeted to researchers more than to different kinds of decision makers. While more in-depth layers of information can always be added to satisfy needs of different audiences, the proposed tools could favor a quick interpretation of articulated scientific data by both decision makers and researchers.

Keywords: information; quantitative qualitative; health; health interventions; eunethta multi; qualitative information

Journal Title: International Journal of Technology Assessment in Health Care
Year Published: 2022

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