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A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022

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Abstract Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April… Click to show full abstract

Abstract Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.

Keywords: influenza; april 2022; h3n2 influenza; community; high attack; large h3n2

Journal Title: Epidemiology and Infection
Year Published: 2023

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