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Dissecting the Cellular Behaviour of Colorectal Cancer via Multimodal Imaging and Correlative Microscopy

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These days, the common ground between structural cell biology and molecular biology continues to grow thanks to the biomolecular insights offered by correlative microscopy (CM). CM utilizes the latest advances… Click to show full abstract

These days, the common ground between structural cell biology and molecular biology continues to grow thanks to the biomolecular insights offered by correlative microscopy (CM). CM utilizes the latest advances in contemporary multimodal imaging approaches that are now capable of filling in the missing pieces of the puzzle. CM allows us to interrogate a sample’s fine structure from the nanoto micrometre scale in a way that is impossible with any one technique alone [1]. The rapidly expanding CM toolset delivers a strong degree of confidence in the observed structures of interest as insights obtained from one microscopy approach can be directly interrogated by other imaging modalities [2].

Keywords: microscopy; multimodal imaging; cellular behaviour; biology; correlative microscopy; dissecting cellular

Journal Title: Microscopy and Microanalysis
Year Published: 2017

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