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Inductive Coupling and Flow for Increased NMR Sensitivity.

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A device is proposed to enhance the NMR sensitivity of slowly relaxing nuclei, taking advantage of a controlled solution flow within a microfluidic circuit and microsized NMR detection. Unlike our… Click to show full abstract

A device is proposed to enhance the NMR sensitivity of slowly relaxing nuclei, taking advantage of a controlled solution flow within a microfluidic circuit and microsized NMR detection. Unlike our previous work ( Carret et al. Anal. Chem. 2017 , 89 ( 5 ), 2995 - 3000 ), this setup can be easily installed on any commercial NMR probehead as it uses induction between the commercial antenna and the microcoil. Such a system leads to a significant gain in sensitivity per time unit for slowly relaxing nuclei while preserving the capabilities of the host probehead.

Keywords: coupling flow; nmr sensitivity; sensitivity; flow increased; inductive coupling

Journal Title: Analytical chemistry
Year Published: 2018

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