LAUSR

Colchicine is highly toxic to creature, and sensitively detecting of colchicine is of profound significance in the pharmaceutical, clinic, food and breeding industries. We herein designed and constructed a unique luminescent indium-organic framework {[(CH3)2NH2][In(L)]•9DMF}n (V105) via in-situ ligand-mediated method, which possesses a two-fold interpenetrated 3D anionic framework. Due to the large channels existed in the framework with the size of 12 Å×14 Å, V105 can rapidly remove harmful cationic dyes from water in few minutes. Importantly, luminescent experiments demonstrate that V105 can selectively detect colchicine with high sensitivity in water, and the limit of detection (LOD) can reach 1.0×10-7 M. To our knowledge, this is the first example of MOFs-based luminescent sensor for detecting colchicine.