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We present a novel statistical learning method for studying context-dependent error rates in error-prone polymerase chain reaction (PCR) experiments. We demonstrate the method by applying it to error-prone PCR sequencing… Click to show full abstract
We present a novel statistical learning method for studying context-dependent error rates in error-prone polymerase chain reaction (PCR) experiments. We demonstrate the method by applying it to error-prone PCR sequencing data and show how it may be exploited to improve the evolvability of genes in protein engineering.
Keywords:
chain reaction;
polymerase chain;
error prone;
context dependent;
prone polymerase
Journal Title: Biochemistry
Year Published: 2022
Link to full text (if available)
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Journal Title: Biochemistry
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!