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Despite the resolution revolution of cryo-EM, structures of small membrane proteins ( Click to show full abstract
Despite the resolution revolution of cryo-EM, structures of small membrane proteins (<80 kDa) are still understudied. These proteins are notoriously reluctant to structure determination by single-particle cryo-EM. Protein fusion might represent a plausible strategy to overcome such difficulties. This Perspective enumerates recent exemplary progress and discusses the future potential of the protein fusion strategy.
Keywords:
fusion;
membrane proteins;
structure determination;
protein fusion;
strategy;
small membrane
Journal Title: Biochemistry
Year Published: 2022
Link to full text (if available)
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Journal Title: Biochemistry
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!