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A unique chemically induced proximity method is engineered based on mutant antibody VL domain using a fluorogenic malachite green derivative as the inducer, which gives fluorescent signals upon VL domain… Click to show full abstract
A unique chemically induced proximity method is engineered based on mutant antibody VL domain using a fluorogenic malachite green derivative as the inducer, which gives fluorescent signals upon VL domain dimerization while simultaneously inducing downstream biological effects.
Keywords:
protein;
green derivative;
malachite green;
self reporting;
chemically induced;
proximity
Journal Title: Bioconjugate chemistry
Year Published: 2018
Link to full text (if available)
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Journal Title: Bioconjugate chemistry
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!