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Impact of Metal-Organic Frameworks on Protein Expression.

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The influence of excessive metal-organic frameworks (MOFs) on the translation process was investigated in this study. Different concentrations and sizes of MOFs were tested through adding them to a cell-free… Click to show full abstract

The influence of excessive metal-organic frameworks (MOFs) on the translation process was investigated in this study. Different concentrations and sizes of MOFs were tested through adding them to a cell-free expression system and observing the downstream expression signal. Furthermore, a proteomics analysis has been employed to explore and reveal the influence of MOFs on the protein expression, which can provide significant referential value for developing a delivery system with MOFs.

Keywords: protein expression; organic frameworks; impact metal; metal organic

Journal Title: Chemical research in toxicology
Year Published: 2021

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