LAUSR

The Human Microbiome Project has prompted unprecedented advancement to microbiome science. Personalized microbiome modulation with precision (PMMP) is one of the emerging yet challenging field in future microbiome research. Carbohydrate-based prebiotics (CBPs) have been shown to modulate gut microbiome in various extents by their different structural characteristics such as degree of polymerization, branching, glycosidic linkage, monosaccharide profile, and chemical modification. Subsequently, a targeted modulation of microbiome might be achieved by using CBPs with specific structure. A multi-dimensional database can be established based on the structure-microbiome (SMR) and structure-microbial-marker (SMMR) relationships. Such relationships could facilitate the development of synbiotics and PMMP.