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Enzyme Free Energy Diagrams: Enzyme–Substrate Binding Is Always Spontaneous

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In at least two papers published in this Journal, enzyme free energy diagrams were presented showing enzyme–substrate binding to be nonspontaneous. I present here several different approaches showi... Click to show full abstract

In at least two papers published in this Journal, enzyme free energy diagrams were presented showing enzyme–substrate binding to be nonspontaneous. I present here several different approaches showi...

Keywords: enzyme substrate; enzyme free; substrate binding; energy diagrams; free energy

Journal Title: Journal of Chemical Education
Year Published: 2021

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