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Chemical investigation of an EtOH extract of the twigs and leaves of Croton damayeshu afforded 10 new tigliane diterpenoids, crodamoids A-J (1-10), along with five known compounds. Their structures were… Click to show full abstract
Chemical investigation of an EtOH extract of the twigs and leaves of Croton damayeshu afforded 10 new tigliane diterpenoids, crodamoids A-J (1-10), along with five known compounds. Their structures were elucidated by physical data analysis. Compounds 8, 9, and 15 displayed cytotoxic effects against two human tumor cell lines, A549 and HL-60 (IC50: 0.9-2.4 μM).
Keywords:
tigliane diterpenoids;
diterpenoids croton;
croton damayeshu;
cytotoxic tigliane
Journal Title: Journal of natural products
Year Published: 2019
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Journal Title: Journal of natural products
Year Published: 2019
Link to full text (if available)
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recommendations!