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Oxetane Intermediate during a Direct Aldol Reaction: Stereoselective [5 + 1] Annulation Affording Tetralines.

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An oxetane intermediate during a direct aldol reaction was trapped with an internal aryl group to yield trans-tetraline products. The contribution of the oxetane intermediate was confirmed by 18O-isotope labeling… Click to show full abstract

An oxetane intermediate during a direct aldol reaction was trapped with an internal aryl group to yield trans-tetraline products. The contribution of the oxetane intermediate was confirmed by 18O-isotope labeling experiments.

Keywords: reaction stereoselective; oxetane intermediate; intermediate direct; aldol reaction; direct aldol

Journal Title: Organic letters
Year Published: 2020

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