The synthesis of 1,2,4-triazolium tetrafluoroborates under electrochemical conditions is reported. The reaction is performed with stoichiometric amounts of HBF4, which converts starting materials to their corresponding cationic forms due to… Click to show full abstract
The synthesis of 1,2,4-triazolium tetrafluoroborates under electrochemical conditions is reported. The reaction is performed with stoichiometric amounts of HBF4, which converts starting materials to their corresponding cationic forms due to protonation. As a result, sufficient conductivity is gained in MeOH, CD3OD, and EtOH, and no additional supporting electrolyte is required. Agrochemical fungicide, (±)-triticonazole (1), is transformed in this manner into 2a, an O-methylated potential intermediate involved in the metabolism of 1, in 42% yield on a gram scale.
               
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