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Photocatalytic Synthesis of Quinolines via Povarov Reaction under Oxidant-Free Conditions.

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We describe here an approach for synthesizing quinolines either from N-alkyl anilines or from anilines and aldehydes. A dual-catalyst system consisting of a photocatalyst and a proton reduction cocatalyst is… Click to show full abstract

We describe here an approach for synthesizing quinolines either from N-alkyl anilines or from anilines and aldehydes. A dual-catalyst system consisting of a photocatalyst and a proton reduction cocatalyst is employed. Without the use of any sacrificial oxidant and under extremely mild conditions, the reactions afford quinolines in excellent yields and produce H2 as a byproduct.

Keywords: photocatalytic synthesis; povarov reaction; via povarov; quinolines via; synthesis quinolines; reaction oxidant

Journal Title: Organic letters
Year Published: 2022

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