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We herein report a synergetic chiral primary amine and rhodium catalysis for asymmetric coupling of β-ketocarbonyls and alkynes. A series of β-ketocarbonyls could be applied to afford linear allylation products,… Click to show full abstract
We herein report a synergetic chiral primary amine and rhodium catalysis for asymmetric coupling of β-ketocarbonyls and alkynes. A series of β-ketocarbonyls could be applied to afford linear allylation products, bearing all-carbon quaternary centers in high regio- and enantioselectivities.
Keywords:
asymmetric coupling;
ketocarbonyls alkynes;
ketocarbonyls;
coupling ketocarbonyls;
chiral primary;
primary amine
Journal Title: Organic letters
Year Published: 2022
Link to full text (if available)
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Journal Title: Organic letters
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!