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Total Synthesis of (+)-Gilbertine: A Cyclopentanone-Based Approach.

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From methyl jasmonate, the concise asymmetric total synthesis of uleine alkaloid gilbertine was reported. The synthesis demonstrated the power of a cyclopentanone-based approach involving the coupling of 2-aminobenzaldehyde and diazo-cyclopentanone… Click to show full abstract

From methyl jasmonate, the concise asymmetric total synthesis of uleine alkaloid gilbertine was reported. The synthesis demonstrated the power of a cyclopentanone-based approach involving the coupling of 2-aminobenzaldehyde and diazo-cyclopentanone for the rapid assembly of the hydrocarbazole natural product.

Keywords: cyclopentanone based; based approach; synthesis; cyclopentanone; gilbertine; total synthesis

Journal Title: Organic letters
Year Published: 2022

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