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Pd-Catalyzed Borylsilylative Cyclization of 1,6-Allenynes.

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A Pd-catalyzed borylsilylative cyclization of 1,6-allenynes with PhMe2SiBpin was developed. This method provides a practical and general method to afford the carbocycles and heterocycles bearing silyl and boryl groups with… Click to show full abstract

A Pd-catalyzed borylsilylative cyclization of 1,6-allenynes with PhMe2SiBpin was developed. This method provides a practical and general method to afford the carbocycles and heterocycles bearing silyl and boryl groups with excellent regioselectivities and stereoselectivities in high to excellent yields.

Keywords: cyclization allenynes; borylsilylative cyclization; catalyzed borylsilylative

Journal Title: Organic letters
Year Published: 2022

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