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Herein, we report that palladium catalyzes the borylative cyclization of α-(2-bromoaryl) ketones to afford 1,2-benzoxaborinines. The developed system is compatible with a variety of functionalities (Me, t-Bu, OMe, NMe2, F,… Click to show full abstract
Herein, we report that palladium catalyzes the borylative cyclization of α-(2-bromoaryl) ketones to afford 1,2-benzoxaborinines. The developed system is compatible with a variety of functionalities (Me, t-Bu, OMe, NMe2, F, Cl, CN, CF3, CO2Me, and heteroaryl groups) and is applicable to the synthesis of B-O-containing tri- and tetracyclic fused-ring compounds.
Keywords:
ketones form;
palladium catalyzed;
bromoaryl ketones;
catalyzed borylative;
cyclizations bromoaryl;
borylative cyclizations
Journal Title: Organic letters
Year Published: 2022
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Journal Title: Organic letters
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!