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Electrochemical Isothiocyanation of Primary Amines.

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Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical,… Click to show full abstract

Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical, mild, high-yielding, and supporting-electrolyte-free electrochemical method for the preparation of aliphatic and aromatic isothiocyanates from amine and carbon disulfide.

Keywords: primary amines; isothiocyanation primary; electrochemical isothiocyanation

Journal Title: Organic letters
Year Published: 2023

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