Photo by brunocervera from unsplash
A novel and green photocatalytic strategy for the synthesis of C-4-acylated coumarins with α-keto acids and 3-nitrocoumarin has been developed. This operationally simple protocol works under mild reaction conditions, providing… Click to show full abstract
A novel and green photocatalytic strategy for the synthesis of C-4-acylated coumarins with α-keto acids and 3-nitrocoumarin has been developed. This operationally simple protocol works under mild reaction conditions, providing convenient access to 4-acyl coumarin derivatives. The control experimental results showed that the nitro radical produced by the cleavage of the C-N bond acts as an electron acceptor to complete the photocatalytic cycle, achieving a redox-neutral reaction.
Keywords:
coumarins keto;
decarboxylative acylations;
neutral decarboxylative;
redox neutral;
photoredox catalyzed;
catalyzed redox
Journal Title: Organic letters
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Organic letters
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!