We present a photo- and Cu-mediated 11C cyanation of bench-stable (hetero)aryl thianthrenium salts via an aryl radical addition pathway. The thianthrenium substrates can be readily accessed via C-H functionalization, and… Click to show full abstract
We present a photo- and Cu-mediated 11C cyanation of bench-stable (hetero)aryl thianthrenium salts via an aryl radical addition pathway. The thianthrenium substrates can be readily accessed via C-H functionalization, and the radiocyanation protocol proceeds under mild conditions (<50 °C, 5 min) and can be automated using open-source, readily accessible augmentations to existing radiochemistry equipment.
Keywords:
mediated 11c;
hetero aryl;
thianthrenium;
photo mediated;
11c cyanation;
aryl thianthrenium
Journal Title: Organic letters
Year Published: 2024
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Journal Title: Organic letters
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!