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Hydropyridylation of Olefins by Intramolecular Minisci Reaction.

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An unprecedented cheap, mild and easy methodology for an intramolecular Minisci reaction based on a hydrogen atom transfer (HAT) initiated hydrofunctionalization of olefins was developed. The method is suitable for… Click to show full abstract

An unprecedented cheap, mild and easy methodology for an intramolecular Minisci reaction based on a hydrogen atom transfer (HAT) initiated hydrofunctionalization of olefins was developed. The method is suitable for the construction of unusual dihydropyrano-pyridine and 1,2,3,4-tetrahydronaphthiridine structures and, unlike most similar reactions, does not require exclusion of air from the reaction medium.

Keywords: intramolecular minisci; methodology; hydropyridylation olefins; minisci reaction; reaction; olefins intramolecular

Journal Title: Organic letters
Year Published: 2017

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