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A simple and efficient method was developed for the construction of the medicinally important tetracyclic 3-spirooxindole benzofuranones. In this highly atom- and step-economical one-pot protocol, one quaternary carbon center, two… Click to show full abstract
A simple and efficient method was developed for the construction of the medicinally important tetracyclic 3-spirooxindole benzofuranones. In this highly atom- and step-economical one-pot protocol, one quaternary carbon center, two new cycles, and four new bonds (C-C/C-O/C-N) were formed under simple ligand-free copper-catalyzed conditions through a novel tandem oxidative annulation strategy.
Keywords:
tandem oxidative;
oxidative annulation;
spirooxindole benzofuranones;
tetracyclic spirooxindole;
annulation strategy
Journal Title: Organic letters
Year Published: 2017
Link to full text (if available)
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Journal Title: Organic letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!