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A novel domino oxidative annulation of 2-vinylanilines with internal alkynes was developed to constitute a rare class of cyclopentaquinoline derivatives. This transformation encompasses four σ bonds formation, one quaternary carbon… Click to show full abstract
A novel domino oxidative annulation of 2-vinylanilines with internal alkynes was developed to constitute a rare class of cyclopentaquinoline derivatives. This transformation encompasses four σ bonds formation, one quaternary carbon center construction, and pyridination steps in one pot under identical conditions, which fascinatingly increases the molecular complexity from easily available starting materials.
Keywords:
domino;
pyridination;
palladium catalyzed;
alkenylation amination;
catalyzed domino;
domino alkenylation
Journal Title: Organic letters
Year Published: 2017
Link to full text (if available)
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Journal Title: Organic letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!