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Submonomer Strategy toward Divergent Solid-Phase Synthesis of α-ABpeptoids.

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A novel submonomer solid-phase synthetic method for α-ABpeptoid oligomers is reported. Iterative submonomer coupling and Fukuyama-Mitsunobu alkylation enable facile, divergent synthesis of α-ABpeptoid oligomers substituted with chemically diverse side chains… Click to show full abstract

A novel submonomer solid-phase synthetic method for α-ABpeptoid oligomers is reported. Iterative submonomer coupling and Fukuyama-Mitsunobu alkylation enable facile, divergent synthesis of α-ABpeptoid oligomers substituted with chemically diverse side chains in excellent yields.

Keywords: phase; divergent; solid phase; submonomer strategy; synthesis; strategy toward

Journal Title: Organic letters
Year Published: 2018

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