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An unprecedented Ag-catalyzed [3 + 2]-annulation of cyclopropenones and DMF via C-C bond cleavage is disclosed. This protocol exhibited excellent chemo- and regio-selectivity, and tolerated various functional groups. More importantly,… Click to show full abstract
An unprecedented Ag-catalyzed [3 + 2]-annulation of cyclopropenones and DMF via C-C bond cleavage is disclosed. This protocol exhibited excellent chemo- and regio-selectivity, and tolerated various functional groups. More importantly, DMF served as the C═O bond in the cycloaddition reaction, providing an efficient way to construct γ-aminobutenolides. In addition, transesterification reaction occurred when DMF was replaced by esters.
Keywords:
bond;
bond cleavage;
via bond;
annulation cyclopropenones;
catalyzed annulation
Journal Title: Organic letters
Year Published: 2018
Link to full text (if available)
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Journal Title: Organic letters
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!