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Amide-Directed Cobalt(III)-Catalyzed C-H Amidation of Ferrocenes.

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The amide-directed cobalt(III)-catalyzed C-H amidation of ferrocene carboxamides using 1,4,2-dioxazol-5-ones as robust and efficient amidating reagents has been developed. This reaction proceeds efficiently under mild reaction conditions with good functional… Click to show full abstract

The amide-directed cobalt(III)-catalyzed C-H amidation of ferrocene carboxamides using 1,4,2-dioxazol-5-ones as robust and efficient amidating reagents has been developed. This reaction proceeds efficiently under mild reaction conditions with good functional group tolerance, providing expedient access to a broad range of ferrocenes containing a nitrogen group on the Cp ring.

Keywords: amide directed; catalyzed amidation; directed cobalt; iii catalyzed; cobalt iii

Journal Title: Organic letters
Year Published: 2019

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