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Specific Encapsulation of Acetylcholine Chloride by a Self-Assembled Molecular Capsule with Sulfonamido Moiety.

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New molecular capsule 12, which encapsulates only acetylcholine chloride in the ion-pair form, has been developed. Cavitand 1 with four sulfonamido moieties on the upper rim of tetraimino-cavitand self-assembled to… Click to show full abstract

New molecular capsule 12, which encapsulates only acetylcholine chloride in the ion-pair form, has been developed. Cavitand 1 with four sulfonamido moieties on the upper rim of tetraimino-cavitand self-assembled to form a stable molecular capsule in the presence of an acetylcholine chloride guest through eight intermolecular -NH···O═S hydrogen bonds, two from each of the four paired sulfonamide units.

Keywords: molecular capsule; self assembled; sulfonamido; acetylcholine chloride

Journal Title: Organic letters
Year Published: 2019

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