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Herein, we report a general approach for the efficient construction of three-dimensional bisindolines via oxidative coupling cyclization in an intermolecular manner. This reaction is featured by its operational simplicity, metal-free… Click to show full abstract
Herein, we report a general approach for the efficient construction of three-dimensional bisindolines via oxidative coupling cyclization in an intermolecular manner. This reaction is featured by its operational simplicity, metal-free conditions, lack of protecting group, and high selectivity. Notably, a wide range of anilines are suitable in this intermolecular cyclization, furnishing corresponding bisindolines in up to 98% yield.
Keywords:
construction;
cyclization;
bisindolines via;
oxidative coupling;
via oxidative;
coupling cyclization
Journal Title: Organic letters
Year Published: 2019
Link to full text (if available)
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Journal Title: Organic letters
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!