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All-Atom Simulations Decrypt the Molecular Terms of RNA Catalysis in the Exon-Ligation Step of the Spliceosome

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The spliceosome, a protein-directed metallo-ribozyme, catalyzes premature mRNA splicing via two transesterification reactions. The atomic-level details of the splicing mechanism and the role of the... Click to show full abstract

The spliceosome, a protein-directed metallo-ribozyme, catalyzes premature mRNA splicing via two transesterification reactions. The atomic-level details of the splicing mechanism and the role of the...

Keywords: simulations decrypt; terms rna; molecular terms; catalysis; atom simulations; decrypt molecular

Journal Title: ACS Catalysis
Year Published: 2020

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