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Formamide-Catalyzed Nucleophilic Substitutions: Mechanistic Insight and Rationalization of Catalytic Activity

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Herein, detailed mechanistic investigations into formamide-catalyzed nucleophilic substitution (SN) of alcohols are reported. Alkoxyiminium chlorides and hexafluorophosphates were synthesized and c... Click to show full abstract

Herein, detailed mechanistic investigations into formamide-catalyzed nucleophilic substitution (SN) of alcohols are reported. Alkoxyiminium chlorides and hexafluorophosphates were synthesized and c...

Keywords: catalyzed nucleophilic; mechanistic insight; formamide catalyzed; insight rationalization; substitutions mechanistic; nucleophilic substitutions

Journal Title: ACS Catalysis
Year Published: 2020

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