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A direct introduction of vinyl ethers into C–H bond of heterocycles is reported. For this purpose, decarboxylative direct C–H cross-coupling of 1,3-diazoles with α-carboxyvinyl ethers as coupling partners was achieved… Click to show full abstract
A direct introduction of vinyl ethers into C–H bond of heterocycles is reported. For this purpose, decarboxylative direct C–H cross-coupling of 1,3-diazoles with α-carboxyvinyl ethers as coupling partners was achieved under Pd(0)/Cu(I) cooperative catalysis to produce various α-heteroarylated vinylethers. This methodology was applied to the innovative production of heteroarylated enolizable ketones and naturally occurring bis-oxa(thia)zoles.
Keywords:
alkoxyalkenylation heterocycles;
heterocycles using;
decarboxylative alkoxyalkenylation;
regioselective decarboxylative;
catalyzed regioselective;
using carboxyvinylethers
Journal Title: ACS Catalysis
Year Published: 2017
Link to full text (if available)
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Journal Title: ACS Catalysis
Year Published: 2017
Link to full text (if available)
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recommendations!