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NHC-Catalyzed ε-Umpolung via p-Quinodimethanes and Its Nucleophilic Addition to Ketones

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An unprecedented NHC-catalyzed generation of p-quinodimethanes via e-umpolung of 4-(chloromethyl)benzaldehydes and the following e-addition to active ketones was developed. A series of active keton... Click to show full abstract

An unprecedented NHC-catalyzed generation of p-quinodimethanes via e-umpolung of 4-(chloromethyl)benzaldehydes and the following e-addition to active ketones was developed. A series of active keton...

Keywords: catalyzed umpolung; via quinodimethanes; addition; nhc catalyzed; umpolung via; quinodimethanes nucleophilic

Journal Title: ACS Catalysis
Year Published: 2019

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